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A groundbreaking study published in Diabetologia has dramatically reframed our understanding of type 2 diabetes risk by highlighting obesity’s overwhelming impact. While scientists previously viewed the disease as a complex interplay of genetics, environment, and lifestyle, this research reveals that excess body weight may be the most critical determinant. The study found that individuals with obesity were more than five times more likely to develop type 2 diabetes compared to those maintaining a healthy weight—a risk far exceeding genetic predisposition or lifestyle factors.
Hermina Jakupovic from the University of Copenhagen emphasized the stark implications, noting that genetic and lifestyle risk factors pale in comparison to the diabetes risk posed by obesity. Even individuals with minimal genetic vulnerability to diabetes faced an eight-fold increased risk when carrying excess weight. This research builds upon previous studies exploring modifiable risk factors, providing compelling evidence that weight management could be the most powerful intervention in diabetes prevention.
The findings challenge traditional multifactorial disease models, suggesting that weight alone can be an independent and dominant risk factor. While genetic predisposition doubled diabetes risk and unfavorable lifestyle habits increased risk by 18 percent, obesity emerged as the most significant predictor, underscoring the critical importance of maintaining a healthy body weight.
To read more, click the link below
: https://www.everydayhealth.com/type-2-diabetes/obesity-alone-affects-type-2-diabetes-risk-study/